Emergency Contraceptive
ulipristal acetate
. Presentations . Composition . Indications . Warning . Drug Interactions . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon
ELLAONE 30 mg: tablet (white); box of 1.
Refunded at 65%. - price: 18,60 euro (s).
Laboratory
| p cp |
| Ulipristal acetate | 30 mg |
| Lactose | + |
This drug contains a substance that belongs to the family of progesterone receptor modulators. It prevents progesterone from acting on its receptors. It thus inhibits ovulation and interferes with the processes that predate the fixation of the fertilized egg in the uterus. This is not a method of terminating pregnancy.
It is used for emergency contraception, in particular in the following cases:
- forgetting or breaking a condom,
- delay in taking the usual contraceptive tablet beyond the acceptable time limit (see this time limit in your contraceptive pill form),
- loss of an IUD spontaneously expelled from the uterus,
- displacement or early withdrawal of a vaginal diaphragm or a contraceptive cape,
- doubt about the good practice of the method of interrupted coitus,
- error of date when using periodic abstinence method (temperature method),
- sexual relationship resulting from rape.
Treatment is possible within 5 days of the potentially fertile relationship. It has no action on the transmission of sexually transmitted infections.
This medicinal product is for exceptional use and can not constitute a regular method of contraception. It does not have a preventive effect for subsequent intercourse and may disrupt current hormonal contraception. Local contraception (preservative, spermicide) should be used until the end of the current cycle.
This emergency contraception is not totally effective: a pregnancy can occur despite the treatment. In case of delayed periods of more than 7 days, a pregnancy test will show whether this delay is due to a progressive pregnancy or hormonal disruption.
In case of abdominal pain or abnormal bleeding around the expected date of menstruation, also perform a pregnancy test and consult your doctor if your test is positive. A diagnosis of
ectopic pregnancy should be made by ultrasound.
Repeated use of this medication during the same cycle should be avoided.
Precautions are necessary in cases of severe asthma.
Due to its potential adverse effects, this medication may not be compatible with driving or handling dangerous machinery. Be sure to take the first few times that you are taking this medicine before you drive or use a machine.
Contraceptive efficacy of this drug may be impaired if you are taking an
enzyme inducer .
Pregnancy : The use of this medication during pregnancy is contraindicated.
Breastfeeding: The punctual use of this medication does not contraindicate the continuation of the breast-feeding. It is recommended to breastfeed just before taking the medication and to avoid breastfeeding for the next 36 hours.
This medicine may be taken with or without food.
Usual dosage:
- Female over 18: take 1 tablet as soon as possible after unprotected intercourse, and at the latest within 5 days of the report.
If vomiting occurs within 3 hours of taking, get another can and take another tablet.
This medication can be taken at any time during the cycle.
Transient hormonal dysregulation: early or delayed menstruation, intermittent bleeding outside menstruation, breast tension.
Nausea, vomiting, abdominal pain.
Dizziness , headache, tiredness, mood disorders.
ectopic pregnancy
Pregnancy developing outside the uterus: during a normal pregnancy, the egg is fertilized in the fallopian tube by a spermatozoon; it should normally progress to the uterus where it is attached to the endometrium. In some cases, this progression is stopped and the egg develops in the proboscis, which is likely to rupture. This is an ectopic pregnancy diagnosed by ultrasound and requires surgery. The signs suggestive of ectopic pregnancy are lower abdominal pain and intermittent bleeding in a woman who has a positive pregnancy test.
enzymatic inducer
The liver, a true chemical plant in the body, ensures the elimination or destruction of many drugs.
Some substances stimulate the hepatic enzymes that provide this elimination function. These substances are enzymatic inducers, and their consumption can reduce the blood concentration of drugs sensitive to their action, diminishing or even canceling their effect. An increase in the dosage of the drug often makes it possible to compensate for the effect of the joint use of an enzyme inducer, but the risk of inefficiency sometimes leads to discouragement of their association. This is the case for oral contraceptives ("pills"), which may lose their effectiveness if they are combined with the regular intake of an enzyme inducer.
The risk is mentioned in the section Drug Interactions when a drug is likely to be significantly modified by the use of an enzyme inducer.
The main enzymatic inducers are usually themselves medicines:
- anti-epileptic drugs (anticonvulsants): carbamazepine, phenobarbital, phenytoin, primidone;
- antituberculosis drug: rifabutin, rifampicin;
- antifungal: griseofulvin.
Other substances may have an enzymatic inducing effect:
- St. John's wort, a plant contained in certain preparations;
- tobacco and alcohol.
Dizziness
Symptom that can mean an impression of loss of balance (common sense) or, more strictly, a sense of rotation on oneself or the environment (medical sense).