Mylan Oxomemazine 0.33 mg 150 ml

For warnings, precautions for use and contraindications, please consult the instructions for use.

Syrup Oxomemazine Mylan 150ML

Antihistamine antitussive medicine used for dry coughs at night that prevent sleep.

The cough is a reflex of sudden and forced expiration of air, which must make it possible to "clean" the respiratory tract. Unlike the so-called wet cough, the dry cough does not produce sputum (it is non-productive). This is most often an irritating cough.

Description of oxomemazine 0.33mg / ml Mylan syrup 150ml

Non-prescription medicine indicated for the symptomatic treatment of bothersome non-productive coughs, in particular predominantly nocturnal.

Allergic cough and asthma also lead to chronic coughs. Asthma is a common cause of chronic cough in children and adults. It affects 15 to 50% of chronic coughs depending on age. In some people with mild asthma, cough is the only symptom. Often, it is nocturnal or morning. In children, this cough may be present for many years before asthma develops.

In itself, dry cough is not a disease. It is a symptom of various pathologies, the first of which are infections, especially viral ones: colds, flu and bronchitis. But also sinusitis or chronic rhinitis: “there are then formed in the nose some secretions charged with infectious agents which, during the night, descend into the bronchi and irritate them. When you wake up in the morning, you start coughing,” explains the pulmonologist.

Using advice and opinion on oxomemazine 0.33mg / ml Mylan syrup 150ml

We advise you in alternative treatment of natural food supplements to fight effectively against coughs , sore throats and flu-like states .

RESERVED FOR ADULTS AND CHILDREN OVER 2 YEARS.

Dry cough is a very common reason for medical consultation. It is not a disease, but a symptom, which is banal in itself but can have multiple causes.

Oral route. Use the measuring cup.

In adults and children over 40 kg (i.e. 12 years):

10 ml per dose, 4 times a day.

In children:

The daily dosage depends on the weight of the child (1 ml of syrup per kg of body weight and per day), either as an indication:

• Child from 13 to 20 kg (i.e. 2 to 6 years) : 5 ml per dose, 2 to 3 times a day,
• Child from 20 to 30 kg (i.e. 6 to 10 years) : 10 ml per dose, 2 to 3 times a day,
• Child from 30 to 40 kg (i.e. 10 to 12 years) : 10 ml per dose, 3 to 4 times a day.

The catches are to be renewed if necessary and spaced at least 4 hours apart.

Evening intake should be preferred (medication to be taken in the evening or at night) because of the sedative effect, especially at the start of treatment, of oxomemazine.

Composition of oxomemazine 0.33mg/ml Mylan syrup 150ml

Precaution for use with oxomemazine 0.33mg / ml Mylan syrup 150ml

This non-prescription medication is CONTRAINDICATED in the following cases:

hypersensitivity to one of the constituents, and in particular to antihistamines,

- due to the presence of oxomemazine:

• infant (less than 2 years old),
• history of agranulocytosis,
• risk of urinary retention linked to urethro-prostatic disorders,
• risk of angle closure glaucoma.

Interactions with Oxomemazine Mylan Syrup

The interactions mentioned are related to the presence of oxomemazine.

Combinations not recommended

+ Alcohol

Enhancement by alcohol of the sedative effect of H1 antihistamines. Impaired alertness can make driving vehicles and using machines dangerous.

Avoid taking alcoholic beverages and medicines containing alcohol.

Other non-prescription sedative drugs

Potentiation of the sedative effect of H1 antihistamines.

+ Sultopride

Increased risk of ventricular arrhythmias, in particular torsade de pointes, by the addition of electrophysiological effects.

Associations to consider

+ Other central nervous system depressants

(Sedative antidepressants, barbiturates, benzodiazepines, clonidine and related drugs, hypnotics, morphine derivatives (analgesics and antitussives), methadone, neuroleptics, anxiolytics):

Increase in central depression. Impaired alertness can make driving vehicles and using machines dangerous.

+ Atropine and other atropine substances

(Imipramine antidepressants, anticholinergic antiparkinsonians, atropine antispasmodics, disopyramide, phenothiazine neuroleptics):

Addition of atropine adverse effects such as urinary retention, constipation, dry mouth.

Presentation of oxomemazine 0.33mg / ml Mylan syrup 150ml

150ml syrup

Pharmacovigilance Report an adverse drug reaction(s)

Download PDF leaflet

Antitussive antihistamine

This medication is a generic of TOPLEXIL

. Presentations . Composition . Indications . Contraindications . Warning . Drug Interactions . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon

PRESENTATIONS ^(summary)

OXOMÉMAZINE BIOGARAN: syrup (caramel flavor); 150 ml bottle with measuring cup.
Refunded at 15%. - price: 1,84 euro (s).

OXOMÉMAZINE BIOGARAN without sugar: oral solution (caramel flavoring); 150 ml bottle with measuring cup.
Refunded at 15%. - price: 1,84 euro (s).

Biogaran Laboratory

COMPOSITION ^(summary)

	p 5 ml	p 5 ml
oxomemazine	1.65 mg	1.65 mg
Sucrose	3.7 g

INDICATIONS ^(summary)

This medication contains an antihistamine from the family of phenothiazines. It has antitussive and sedative properties .
It is used in the symptomatic treatment of dry coughs, especially those that occur at night.

CONTRAINDICATIONS ^(summary)

This medication should not be used in the following cases:

• antecedent of agranulocytosis ,
  
• risk of closed-angle glaucoma ,
  
• risk of blocking urine bound to an adenoma of the prostate ,
  
• child under 2 years of age.
  

WARNING ^(Contents)

This medication is not suitable for the treatment of fatty cough, which is a normal defense mechanism of the body allowing the evacuation of the mucus present in the bronchi.
Cough is a symptom that can reveal many diseases ( allergies , heart disease, lung, digestive ...): consult your doctor if it persists for more than a few days.
Precautions are necessary in case of heart disease, epilepsy , hepatic insufficiency, renal insufficiency and in the elderly, especially in case of chronic constipation, prostate adenoma , tendency to dizziness or drops Of voltage.
Oxomemazine, like other drugs in the phenothiazine family, is likely to cause photosensitization reactions; avoid exposure to sunlight during treatment.
Avoid alcoholic beverages: increased risk of drowsiness.
This medication may induce somnolence, sometimes intense in some people. This drowsiness can be increased by taking alcohol or other sedative drugs. Driving and using hazardous machines are not recommended, especially within hours of taking the medication.

DRUG INTERACTIONS ^(summary)

This medicinal product must not be combined with medicinal products containing cabergoline or quinagolide: the risk of their effects being nullified.
Tell your doctor or pharmacist if you are taking any other medicines that have atropine or sedative effects (tranquillizers, sleeping pills, some cough or pain medications containing opioids , antidepressants , neuroleptics, etc.).

PREGNANCY AND BREAST-FEEDING ^(summary)

Pregnancy :
The effect of this medication during pregnancy is not well known: only your doctor can evaluate the possible risk of its use in your case.
In case of termination of pregnancy, monitoring of the newborn may be necessary.

Breastfeeding:
The data currently available do not indicate whether this drug passes into breast milk: as a precaution, it is not recommended during breast-feeding.

DIRECTIONS FOR USE AND DOSAGE ^(summary)

This medication is taken preferably at the time of the cough, by spacing the catches of at least 4 hours. Evening catches should be preferred because of the risk of drowsiness.

Usual dosage:

• Adult and child over 40 kg (over 12 years): 1 cup graduated to 10 ml, 4 times a day.
  
• Child 30 to 40 kg (approximately 10 to 12 years): 1 cup graduated to 10 ml, 3 or 4 times a day.
  
• Child of 20 to 30 kg (approximately 6 to 10 years): 1 cup graduated to 10 ml, 2 or 3 times a day.
  
• Child 12 to 20 kg (approximately 2 to 6 years): 1 cup graduated to 5 ml, 2 or 3 times a day.
  

TIPS ^(summary)

If you are a smoker, continuing smoking affects the effectiveness of the treatment.
Simple measures, hot drinks and humidification of the ambient air, allow to calm the dry coughs.

POSSIBLE ADVERSE EFFECTS ^(summary)

Drowsiness.
Atropine effects: dry mouth, difficulty in accommodation , blocked urine, constipation, palpitations .
Orthostatic hypotension , dizziness .
Tremors, poor coordination of movements.
Agitation, confusion of ideas.
Allergic reaction , photosensitization .
Abnormal blood count .

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GLOSSARY ^(summary)

accommodation
"Focus" of the eye, allowing clear vision close up. Presbyopia is the most common disorder of accommodation; some drugs such as atropine may cause passenger accommodation problems.


adenoma of the prostate
Increase in the volume of the prostate gland located under the bladder of the man. This increase in volume is benign, has no relationship to cancer, but can interfere with the passage of urine into the urethra through the gland.
Symptoms that suggest the presence of a prostate adenoma are:

• difficulty urinating (slowness, weakness of the spray);
  
• the need to get up several times at night to urinate;
  
• urges to urinate imperiously and difficult to control.
  

Certain drugs, especially atropinic drugs, may have the undesirable effect of aggravating the discomfort and may lead to a total blockage of the evacuation of the bladder. They are therefore contraindicated or should be used cautiously in men with the symptoms described above.


agranulocytosis
Disappearance of white blood cells. This serious condition prevents the body from reacting to infections. It is most often due to the toxicity of a drug on the bone marrow, where the blood cells are made.


alcohol
General name designating a family of substances that have the property of being able to be mixed with water and fatty substances. The most common alcohol is ethyl alcohol (ethanol), but there are many other alcohols: methanol, butanol, etc. The degree of alcoholic solution corresponds to the volume of pure alcohol present in 100 ml of solution, knowing that 1 glass of wine or 1/2 of beer (25 cl) contains about 8 g of alcohol.
When alcohol is used as an antiseptic, an unpleasant odor denaturant is often added to prevent drinking. Contrary to a widespread belief, alcohol at 70o (or even at 60o) is a better antiseptic than alcohol at 90o.


allergy
Skin reaction (itching, pimples, swelling) or general discomfort occurring after contact with a particular substance, use of a medication, or ingestion of food. The main forms of allergy are eczema, urticaria, asthma, angioedema and allergic shock (anaphylactic shock). Food allergy can also result in digestive disorders.


antecedent
Affection healed or always in evolution. The antecedent may be personal or family. The background is the history of a person's health.


antidepressants
Medication that works against depression. Some antidepressants are also used to combat obsessive-compulsive disorder, generalized anxiety, certain rebellious pain, enuresis, etc.
Depending on their mode of action and adverse effects, antidepressants are divided into different families: imipraminic antidepressants, serotonin reuptake inhibitors, selective or non-selective MAOIs. Finally, other antidepressants do not belong to any of these families, because they possess original properties.
The mode of action of antidepressants has two main aspects: the relief of moral suffering and the fight against inhibition which removes all will to action from the depressed. There may be a time lag between these two effects: moral suffering may persist, while the capacity for action reappears. During this short period, the risk of suicide in some depressed people can be increased. The physician takes it into account in its prescription (possible association with a tranquillizer) and it must imperatively be respected.


antihistamine
Medication that opposes different effects of histamine. Two main types exist: antihistamines type H1 (antiallergic) and antihistamines type H2 (gastric antiulcer). Some antihistamines of type H1 are sedative, others do not alter vigilance.


atropine
Medication with effects similar to those of atropine. Atropinics fight spasms and diarrhea. Adverse effects of atropinic drugs include: thickening of bronchial secretions, dry mouth and mucous membranes, constipation, risk of urine blockage and acute glaucoma in susceptible persons, accommodation disorders, abnormal sensitivity to light by dilation of the pupil. Taking several atropine medicines increases the risk of adverse effects. In the event of overdose or accidental ingestion, the following signs may also appear: red and warm skin, fever, acceleration of breathing, fall or, on the contrary, elevated blood pressure, agitation, hallucinations, poor coordination of movements. Emergency care should be given to your doctor or, if not available, call 15, 112 or an emergency medical service.
In addition to atropine and its derivatives, other drugs have atropine effects: imipraminic antidepressants, some antihistamines, antispasmodics, antiparkinsonian and neuroleptic.


epilepsy
A chronic seizure disorder associated with abnormal electrical activity of a group of brain cells. Its manifestations, varying in intensity, range from the sudden drop in attention (absences, or small evil) to loss of consciousness accompanied by abnormal muscle movements (convulsions, or great evil). Partial epilepsy, as its name implies, does not concern the whole body: the jerky movements only touch one or more muscle groups.


glaucoma
Disease characterized by increased pressure of the fluids contained in the eye (intraocular hypertension).
This general term covers two totally different affections:

• Open angle glaucoma or chronic glaucoma is the most frequent; it is generally symptom-free, detected by the measurement of intraocular tension in the ophthalmologist. It does not cause acute seizures, and treatment relies primarily on beta-blocking eye drops. People with open-angle glaucoma should not use cortisone derivatives without prior ophthalmologic advice.
  
• Closed-angle glaucoma or acute glaucoma is more rare. Between seizures, intraocular tension is normal. But the inadvertent use of atropine medicines (especially eye drops) causes an acute crisis of intraocular hypertension which can permanently damage the retina in a few hours. It is an ophthalmological emergency that is recognized by a brutally red eye, horribly painful, hard as a glass ball, and whose vision becomes blurred.
  

The angle in question in these two affections is the irido-corneal angle. It is indeed between the iris and the cornea that is located the system of evacuation of the liquids of the eye. A slightly open (closed) angle exposes a total obstruction of the evacuation system. This obstruction can occur when the iris is opened to the maximum (mydriasis) under the effect of an atropinic drug: the iris then comes to be attached to the cornea.
Contraindications for atropine medicines are limited to those who have already had closed-angle glaucoma or who have been detected by an ophthalmologist. Those who suffer from chronic open-angle glaucoma are not affected by these contraindications.


Orthostatic hypotension
Reduced blood pressure when changing from elongated to standing. Due mostly to drugs, orthostatic hypotension results in dizziness with risk of fall, especially in the elderly. These disturbances can be prevented by avoiding sudden changes of position: sit for a few moments at the edge of the bed before standing up, slowly rising from a seat with a support before moving.
Wearing compression stockings, which prevents blood from flowing back to the legs while standing, is also used to treat orthostatic hypotension.


Hepatic insufficiency
Inability of the liver to perform its function, which is essentially the elimination of some waste, but also the synthesis of many biological substances essential to the body: albumin, cholesterol and coagulation factors (vitamin K, etc.).


renal failure
Inability of the kidneys to eliminate waste or medicinal substances. Advanced renal insufficiency does not necessarily result in a decrease in the amount of urine excreted. Only a blood test and creatinine dosage may reveal this disease.


neuroleptics
Family of medicines used in the treatment of certain nervous disorders or various symptoms: digestive disorders, menopausal disorders, etc.


new born
Child less than one month old.


blood count
The count measures the number of red blood cells (red blood cells), white blood cells (leukocytes) and platelets in the blood. The blood formula specifies the percentage of different white blood cells: neutrophils, eosinophils, basophils, lymphocytes, monocytes.
Abbreviation: NFS.


opiates
A chemical family that includes opium and its derivatives. In addition to drugs such as opium or heroin, the opiate family includes morphine (strong analgesic), codeine (antitussive and analgesic) and many other substances.


palpitations
Abnormal perception of irregular heartbeat.


photosensitivity
Abnormal sensitivity of the skin to light or ultraviolet rays due to a drug or a natural or chemical substance.


Allergic reaction
Reaction due to hypersensitivity of the organism to a drug. Allergic reactions can take a wide variety of aspects: urticaria, angioedema, eczema, eruption of pimples resembling measles, etc. Anaphylactic shock is a generalized allergic reaction that causes discomfort due to a sudden drop in blood pressure.


sedative

• Quiets, calms down.
  
• Medication belonging to different families: anxiolytics, hypnotics, analgesics, cough suppressants, antiepileptics, neuroleptics, etc. but also antidepressants, antihistamines H1, antihypertensives. A sedative can be responsible for drowsiness and increase the effects of alcohol.
  

symptom
Trouble felt by a person with an illness. The same symptom can translate different diseases and the same disease does not necessarily give the same symptoms in all the patients.


symptomatic treatment
Treatment that suppresses or alleviates the symptoms of a disease without addressing its cause.


dizziness
Symptom that can mean an impression of loss of balance (common sense) or, more strictly, a sense of rotation on oneself or the environment (medical sense).