Mildac 600mg Depressive manifestations 15 Tablets

Mildac 600mg St. John's Wort: Relieve your depressive manifestations naturally

Minor depression

It is a chronic disorder (lasting at least two years) defined as follows:

• depressed mood most of the day, more than every other day for two years;
• during the depressive phases, at least two of the following symptoms are present:

• loss of appetite or on the contrary hyperphagia,
• insomnia or hypersomnia,
• low energy or fatigue,
• low self-esteem,
• difficulty concentrating or making decisions,
• feeling of loss of hope.

• the patient is never more than 2 consecutive months without presenting these symptoms;
• these symptoms lead to suffering and discomfort in socio-professional life.

Mildac 600mg St. John's Wort: Find your emotional balance

Mediflor Mildac 600mg from Mediflor laboratories is a herbal medicine in the form of coated tablets used in the short-term treatment of states of transient sadness and accompanied by loss of interest and sleep disorders.

Reserved for adults, Mediflor Mildac 600mg Tablets is traditionally used in mild and transient depressive manifestations.

Relieve your depressive manifestations and rediscover the joy of living

Fight the symptoms of depression with Mildac

Say goodbye to depression and regain your vitality with Mildac 600mg St. John's Wort. If you suffer from depressive manifestations such as persistent sadness, constant fatigue and loss of interest in the activities you enjoy, this natural dietary supplement is for you. Mildac contains a standardized extract of St. John's wort , a plant with antidepressant properties recognized for centuries.

Thanks to its concentrated formula, each Mildac 600mg tablet provides you with the optimal dose of St. John's Wort to relieve your symptoms of depression. St. John's wort works by balancing neurotransmitters in the brain, which helps improve your mood and reduce anxiety. By taking Mildac regularly, you will experience a decrease in sadness and apathy, as well as an increase in energy and optimism.

A natural solution without unwanted side effects

One of the major benefits of Mildac 600mg St. John's Wort is its all-natural nature. Unlike prescription drugs, Mildac is a dietary supplement made from herbal extracts, which means it does not have the common side effects associated with synthetic antidepressants.

Thanks to the medicinal plant St. John's wort , Mildac is a natural and safe alternative to treat mild to moderate depressive manifestations. You can feel relieved knowing you don't have to worry about unwanted side effects like drowsiness, weight gain, or addiction. Opt for a natural and safe approach with Mildac to regain your emotional well-being.

How to use Mildac for optimal results?

Recommended dosage

To get the best results from Mildac 600mg St. John's Wort, it is essential to follow the recommended dosage instructions. We advise you to take one tablet a day with a glass of water, preferably in the morning. Regular intake of Mildac is important to maintain a stable emotional balance and reduced depressive symptoms.

Remember that the effects of Mildac may take some time to fully manifest. It is therefore recommended to continue using the product for at least 4 to 6 weeks before evaluating the results. Be patient and consistent in your approach to obtaining the full benefits of Mildac. Do not exceed 15 days of treatment without medical advice.

Reserved for adults. Medicine, read the leaflet carefully, ask your pharmacist for advice, if the symptoms persist consult your doctor. Store at a temperature not exceeding +25°C.

Integrate Mildac into your daily routine

To optimize the effects of Mildac, it is recommended to incorporate it into a daily wellness routine. Here are some tips to maximize the benefits of Mildac:

• Establish a regular routine: Take your Mildac tablet at the same time each day, preferably in the morning. This will allow you to maintain a constant concentration of active ingredients in your body.
• Adopt a healthy lifestyle: Complete the action of Mildac by adopting healthy lifestyle habits. Exercise regularly, eat a balanced diet and allow yourself moments of rest and relaxation.
• Pay attention to your emotional well-being: Take the time to connect with your emotions and express yourself. Meditation, journaling or sharing with loved ones can be beneficial practices to promote your emotional balance.

Find your happiness with Mildac 600mg St. John's Wort

A holistic approach to your mental well-being

Mildac 600mg St. John's Wort offers a holistic approach to your mental well-being . By relieving depressive manifestations, this dietary supplement allows you to rediscover your joie de vivre and take full part in all the wonders of life. Don't let depression rob you of your happiness. Choose Mildac and rediscover your inner radiance.

Sustained results for a better quality of life

By using Mildac on a regular and continuous basis, you can expect lasting results. This food supplement works gently to restore your emotional balance, allowing you to enjoy a better quality of life. You will feel more in harmony with yourself, ready to face daily challenges with confidence and serenity.

Take the first step towards a fulfilling life

Don't let depression rule your life. Take the first step towards a fulfilling life by choosing Mildac 600mg St. John's Wort. With its natural formula, its lasting benefits and its ability to relieve depressive manifestations, Mildac is your ally to regain your vitality and your happiness. Don't wait any longer, give yourself the gift of emotional well-being with Mildac.

Composition of mildac 600mg

St. John's wort methanolic dry extract 612 mg. Excipients: Ascorbic acid, microcrystalline cellulose, croscarmellose sodium, iron oxide (E 172), hypromellose, stearic acid, magnesium stearate, sodium saccharin, colloidal silica, titanium dioxide (E 171), talc, vanillin, qsp 1 film-coated tablet .

Precaution for use with mildac 600mg

This drug is contraindicated in the following situation:

In association with :

• Oral anti-coagulants
• Anticonvulsants (ethosuximide, felbamate, fosphenytoin, lamotrigine, phenobarbital, phenytoin, primidone, tiagabine, topiramate, valproic acid, valpromide) except with carbamazepine (see combination not recommended), gabapentin and vigabatrin,
• oral contraceptives,
• Digoxin
• Immunosuppressants (ciclosporin, sirolimus, tacrolimus)
• Protease inhibitors (amprenavir, atazanavir, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir),
• Tyrosine kinase inhibitors
• Irinotecan,
• Theophylline.

Interactions with other medicinal products and other forms of interaction:

Contraindicated combinations :

• Oral anticoagulants: Decrease in plasma concentrations of the oral anticoagulant with risk of reduced efficacy, or even cancellation of the effect, the consequences of which may possibly be serious (thrombotic event). In case of fortuitous association, do not suddenly stop taking St. John's wort but check the INR before then after stopping St. John's wort.
• Anticonvulsants (ethosuximide, felbamate, fosphenytoin, lamotrigine, phenobarbital, phenytoin, primidone, tiagabine, topiramate, valproic acid, valpromide) except with carbamazepine (see combination not recommended), gabapentin and vigabatrin: Risk of decreased plasma concentrations and the effectiveness of the anticonvulsant.
• Oral contraceptives (estroprogestogens, progestogens): Decreased plasma concentrations of oral contraceptives, with risk of reduced efficacy, or even cancellation of the effect. In case of fortuitous association, do not suddenly interrupt the intake of St. John's wort.
• Digoxin: Decrease in digoxinemia, with risk of reduced efficacy, or even cancellation of the effect, the consequences of which may possibly be serious (decompensation of heart failure). In case of fortuitous association, do not suddenly stop taking St. John's wort, but monitor digoxinemia before and after stopping St. John's wort.
• Immunosuppressants (ciclosporin, sirolimus, tacrolimus): Reduction in blood concentrations and in the efficacy of the immunosuppressant (or even cancellation of the effect) with risk of transplant rejection. In case of fortuitous association, do not suddenly stop taking St. John's wort, but monitor the blood concentrations of the immunosuppressant before then after stopping St. John's wort.
• Protease inhibitors (amprenavir, atazanavir, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir): Decrease in plasma concentrations of the protease inhibitor with risk of reduced efficacy, or even cancellation of the effect, including consequences can be potentially serious. In case of fortuitous association, do not suddenly stop taking St. John's wort, but check the effectiveness of the protease inhibitor before and after stopping St. John's wort.
• Tyrosine kinase inhibitors: Decrease in plasma concentrations and efficacy of the tyrosine kinase inhibitor by increasing its metabolism by St. John's wort.
• Irrinotecan: Decreased plasma concentrations of the active metabolite of irinotecan with risk of failure of cytotoxic treatment.
• Theophylline: Decrease in theophyllinemia, with risk of reduced efficacy, or even cancellation of the effect, the consequences of which may possibly be serious (occurring of an obstructive ventilatory disorder). In the event of fortuitous association, do not suddenly interrupt the intake of St. John's wort, but control the theophyllinemia before then after stopping St. John's wort. 

Disadvised combinations :

• Cabamazepine: Risk of reduced plasma concentrations and anticonvulsant efficacy.
• Telithromycin: Decrease in plasma concentrations of telithromycin, with risk of failure of anti-infective treatment, by increased hepatic metabolism of telithromycin by St. John's wort.

Pharmacodynamic interactions :

Combinations subject to precautions for use:

• Serotonin reuptake inhibitor antidepressants (citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline): Risk of onset of serotonin syndrome: diarrhea, tachycardia, sweating, tremors, confusion, even coma. Regular clinical monitoring.
• Non-selective MAOI (iproniazide): Risk of appearance of a serotonergic syndrome: diarrhea, tachycardia, sweating, tremors, confusion, even coma. Regular clinical monitoring.
• Selective MAOI A (moclobemide, toloxatone): Risk of appearance of a serotoninergic syndrome: diarrhoea, tachycardia, sweating, tremors, confusion, even coma. Regular clinical monitoring.
• Linezolid: Risk of appearance of a serotonergic syndrome: diarrhoea, tachycardia, sweating, tremors, confusion, even coma. Regular clinical monitoring.
• Propafenone: Decreased plasma concentrations of propafenone by increasing its hepatic metabolism by St. John's wort

Side effects :

• A few cases of serotonergic syndrome associating nausea, dizziness, headache, anxiety, abdominal pain, agitation, mental confusion) have been reported in the literature in elderly patients treated concomitantly with a serotonin reuptake inhibitor antidepressant and St. John's wort . The syndromes regressed after discontinuation of St. John's wort (see Interactions with other medicinal products and other forms of interaction).
• Digestive disorders and photosensitization type skin reactions have been reported.

Overdose:

No case of overdose has been reported.

Presentation of mildac 600mg cpr 15

Box of 15 tablets.

Our expert opinion in pharmacy

Where do mood disorders come from ?

The mechanisms explaining the occurrence of MDLT remain unknown: many factors seem to come into play. We do know, however, that certain life events or contexts can favor it: professional difficulties (“burn out”), family problems (mourning, breakup. ..), menopause, smoking cessation…

Individual susceptibility certainly plays a determining role. From a physical point of view, mood disorders are accompanied by disturbances in the exchanges between neurotransmitters, these chemical “messengers” of brain neurons (serotonin, norepinephrine, etc.).

Pharmacovigilance Report an adverse drug reaction(s)

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Phytotherapy

St. John's wort

. Presentations . Composition . Indications . Contraindications . Warning . Drug Interactions . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon

PRESENTATIONS ^(summary)

MILDAC 300 mg: tablet; box of 40.
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MILDAC 600 mg: tablet; box of 15.
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Merck Family Medication Laboratory

COMPOSITION ^(summary)

	p cp	p cp
St. John's wort, extract	300 mg	600 mg
Lactose	+

INDICATIONS ^(summary)

This medicine contains an extract of St. John's wort, a plant that has been the subject of scientific research in the treatment of depressive states . Data from these studies indicate that St. John's Wort has activity in the treatment of mild depression. Since these studies have focused on time-limited intake, this drug can not currently be considered a true antidepressant and is recommended only in the treatment of transient depressive states.
It is traditionally used in the treatment of mild and transient depressive manifestations.

CONTRAINDICATIONS ^(summary)

This medication should not be combined with oral anticoagulants , protease inhibitors, or ciclosporin-containing medicines.

WARNING ^(Contents)

Depression is a serious illness that warrants medical advice when the state of sadness is not justified by a major event or when it lasts long after a possible triggering event.
Although this drug is over-the-counter and contains only plant extract, it may cause drug interactions, particularly with oral contraceptives (pills). Its effectiveness should not be overestimated and the use of a "classic" antidepressant , prescribed by a physician, combined with psychological support, may be necessary.

DRUG INTERACTIONS ^(summary)

This medication should not be combined with oral anticoagulants , antiproteases , certain anticonvulsants or ciclosporin: decreased efficacy with St. John's wort, or increased blood levels and risk of overdose if drug is discontinued .
It may interact with oral contraceptives , antidepressants inhibiting serotonin reuptake , triptan antimigraine drugs, and drugs containing digoxin, theophylline, and phenytoin.

PREGNANCY AND BREAST-FEEDING ^(summary)

The effect of this medication during pregnancy or lactation is not well known: only your doctor can evaluate the possible risk of its use in your case.

DIRECTIONS FOR USE AND DOSAGE ^(summary)

The tablets should be swallowed with a glass of water, preferably at regular time.

Usual dosage:

• Adult: 1 tablet 300 mg, 1 to 3 times daily or 1 tablet 600 mg daily, preferably in the morning.
  

TIPS ^(summary)

The treatment of a depressive state , even if light, is not just about taking medication. The support of a professional is often a valuable aid to take a difficult course or reflect on the conscious or unconscious causes that are at the origin of this state.

POSSIBLE ADVERSE EFFECTS ^(summary)

Digestive disorders , photosensitization .

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GLOSSARY ^(summary)

anti coagulants
Medication that prevents blood from coagulating and therefore prevents clots from forming in the blood vessels.
Anticoagulants are used to treat or prevent phlebitis, pulmonary embolism, certain infarcts. They also prevent the formation of clots in the heart during rhythm disorders such as atrial fibrillation or in the case of an artificial heart valve.
There are two main types of anticoagulants:

• oral anticoagulants, which block the action of vitamin K (antivitamin K, or AVK) and whose effectiveness is controlled by a blood test: INR (formerly TP);
  

• injectable anticoagulants derived from heparin, the efficacy of which can be controlled by the blood assay of anti-Xa activity, Howell's Time (TH) or Cephalin Kaolin Time (TCK) depending on the products used. A regular dosage of blood platelets is necessary throughout the life of a heparin derivative.
  

anticonvulsants
Medication used to treat convulsions and various forms of epilepsy. Anticonvulsants are classified as barbiturates (phenobarbital) and non-barbiturates, which are currently the most widely used.


antidepressant
Medication that works against depression. Some antidepressants are also used to combat obsessive-compulsive disorder, generalized anxiety, certain rebellious pain, enuresis, etc.
Depending on their mode of action and adverse effects, antidepressants are divided into different families: imipraminic antidepressants, serotonin reuptake inhibitors, selective or non-selective MAOIs. Finally, other antidepressants do not belong to any of these families, because they possess original properties.
The mode of action of antidepressants has two main aspects: the relief of moral suffering and the fight against inhibition which removes all will to action from the depressed. There may be a time lag between these two effects: moral suffering may persist, while the capacity for action reappears. During this short period, the risk of suicide in some depressed people can be increased. The physician takes it into account in its prescription (possible association with a tranquillizer) and it must imperatively be respected.


protease inhibitors
An antiretroviral drug which acts by blocking an enzyme (protease) necessary for the maturation of the AIDS virus (HIV) in infected cells. This type of drug blocks one of the stages of reproduction of the virus, but does not allow its eradication. It is most often used in combination with other antiretrovirals.


contraceptives
Who opposes conception: oral contraceptive (pill), local (IUD, spermicide, diaphragm and condom).


depressive states
State of moral suffering associating a demotivation, a fatigue, a feeling of uselessness, of self-depreciation. In the absence of treatment, the depressive state may develop into a serious depression with a feeling of incurability, guilt, and a suicidal risk.


inhibitors of serotonin reuptake
Antidepressant increases the amount of serotonin in the brain, limiting its recapture. Some IRSs are also used for the treatment of obsessive compulsive disorder (OCD) and anxiety.
See also: serotonergic antidepressant.


photosensitivity
Abnormal sensitivity of the skin to light or ultraviolet rays due to a drug or a natural or chemical substance.


overdose
Taking an excessive amount of a drug exposes you to an increase in the intensity of adverse effects, or even to the appearance of particular adverse effects.
This overdose may result from accidental or voluntary poisoning for suicide, so consult your local Poison Control Center (listed in the appendix to the book). However, in most cases, overdose is the result of an error in the understanding of the prescription, or the search for an increase in efficacy by exceeding the recommended dosage. Finally, untimely self-medication may lead to excessive absorption of the same substance contained in different drugs. Some drugs are particularly prone to this risk because they are (wrongly) considered to be harmless: vitamins A and D, aspirin, etc. Stopping or decreasing drug intake helps to remove the disorders associated with an overdose.


triptans
Name of a chemical family of vasoconstrictors used in the treatment of migraine. Compared to vasoconstrictors derived from rye ergot, triptans have the advantage of acting more specifically on the arteries of the brain.


Digestive disorders
Set of symptoms indicating irritation or malfunction of the digestive tract. One or more disorders may be present: nausea, vomiting, aerophagia, abdominal pain, heartburn, bloating, flatulence, diarrhea or constipation, etc. Antibiotics can promote candidiasis, often responsible for digestive disorders.