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1 mg/mL Nicotine EG Oral Solution
Over-the-counter medication

1 mg/mL Nicotine EG Oral Solution

Brand : Nicorette Nicorette

Nicotine Spray—Mint Oral Spray Solution—is a medication indicated for the relief of nicotine cravings and nicotine withdrawal symptoms associated with quitting tobacco use.

€25.21 EXCL. VAT €25.74 INCL. VAT
This product is an over-the-counter medication. Please consult the package insert before ordering online.
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Reference : 3400930192771
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What is Nicotine Buccal Spray 1 mg/Dose Oral Solution used for?

If you’re determined to break your nicotine addiction, Nicotine Buccal Spray is here to help. This medication is specifically designed to relieve nicotine cravings and nicotine withdrawal symptoms associated with quitting smoking. We understand how difficult the quitting process can be, which is why Nicorette has developed this effective oral spray to help you regain control over your cravings to smoke.

Quitting smoking can be a difficult step, as it’s often accompanied by unpleasant withdrawal symptoms. Nicorette Oral Spray acts as an essential ally on your journey toward a smoke-free lifestyle. The main benefits of this product are as follows:

Relief from nicotine cravings:

Nicorette Oral Spray is specially formulated to provide immediate relief when you feel an overwhelming urge to smoke. Simply spray a 1 mg dose of nicotine into your mouth to satisfy those cravings and avoid giving in to the temptation to smoke.

Alleviation of withdrawal symptoms:

Nicotine withdrawal syndrome involves a range of symptoms that can vary in severity. Common symptoms include feelings of sadness or even depression, insomnia, irritability, frustration, anger, anxiety, difficulty concentrating, restlessness, a slowed heart rate, increased appetite, sweating, and headaches. Nicorette Oral Spray is designed to alleviate these symptoms, helping you stay focused on your goal of quitting smoking.

Personalized Craving Control:

One of the most beneficial features of Nicorette Oral Spray is its ease of use. You can precisely adjust your nicotine intake to suit your needs. One to two sprays are usually enough to effectively control your cravings. You have the power to decide when and how many doses to use to keep your nicotine addiction under control.

A Safe Alternative to Tobacco:

Nicotine Buccal Spray offersa safe alternative to cigarettes. By avoiding the toxins found in tobacco smoke, you significantly reduce the risks to your health. This means you can continue to satisfy your nicotine dependence without the harmful effects of smoking.

For warnings, precautions, and contraindications, please refer to the package insert.

How to Use This Nicotine Spray?

At the start of treatment, use 1 or 2 sprays of Nicorette at your usual smoking times or when you have a strong craving. Start with one spray, and if the urge to smoke does not go away after a few minutes, use a second spray. If 2 sprays are needed, subsequent doses may consist of 2 consecutive sprays. Many smokers need to use about 1 or 2 sprays every 30 minutes to 1 hour.

For example, if you smoke an average of 15 cigarettes a day, you should use 1 to 2 sprays at least 15 times a day.
After 6 weeks, begin reducing the daily number of sprays.
The maximum dose is 2 sprays per dose, 4 sprays per hour, and 64 sprays per day.
People under 18 years of age should not use Nicorette Spray unless prescribed by a doctor.

Opening the dispenser, unlocking the spray nozzle:

  • Using your thumb, slide the button down until you can push it in with light pressure. Do not press too hard.
  • While pushing the button inward, slide it upward to unlock the top of the dispenser. Then release the button.

Loading the dispenser:
When using the oral spray for the first time, you must first prime the spray. Hold the spray with the nozzle pointing away from yourself and from any adults, children, or animals nearby. Using your index finger, press the top of the dispenser 3 times until a fine mist appears. After 2 days of non-use, you may need to repeat this priming procedure.

Closing the dispenser, blocking the spray nozzle:

  • Slide the button down until you can push it inward.
  • While pushing the button inward, slide the top of the dispenser downward.
  • Release the button. The dispenser is now closed.

To take another dose, repeat the steps above.

Vitamin C and Vitamin E Deficiencies in Tobacco Smokers

Smoking leads to a deficiency invitamin C(ascorbic acid) andvitamin E(tocopherol).
Vitamins E and C are antioxidants capable of neutralizing free radicals produced in our bodies during inflammatory processes (smoking, cancer, Alzheimer’s disease). In fact, the free radicals generated by tobacco smoke gradually destroy the alveolar membranes.
Vitamin E (tocopherol)works synergistically with vitamin C, which explains why vitamin C supplementation significantly reduces the vitamin E deficiency observed in tobacco smokers.
Tobacco smokers consistently have deficiencies in both vitamin E and vitamin C; for these reasons, we recommenddietary supplements rich in vitamin C (acerola)and naturally occurring, bioavailable vitamin E

Share your feedback on the usage instructions and dosage of Nicotine Buccal Spray 1 mg Nicotine x150 with our partner “Verified Reviews” after your purchase.

What is its composition?

Active ingredient: Nicotine.
One spray delivers a dose of 1 mg of nicotine.
Inactive ingredients
glycerol, poloxamer 407, glycine, sodium bicarbonate, pulegone, sucralose, acesulfame potassium, sodium hydroxide, purified water
Flavoring: levomenthol, cooling agent, menthol, menthol carboxamide, aromatic essence, mint flavor

Contraindications:

If you are allergic (hypersensitive) to nicotine or any of the other ingredients in Nicotine EG 1 mg.

Precautions:

Contact your doctor if you experience any of the following symptoms. You may take Nicotine EG 1mg, but you should discuss this with your doctor first if you have:

  • a recent history (< 3 months) of a heart attack or stroke, chest pain (unstable angina), or stable angina, a heart condition affecting your heart rate or rhythm, high blood pressure that is not controlled by medication,
  • a history of allergic reactions characterized by swelling of the lips, face, and throat (angioedema) or itchy skin rashes (hives). In some cases, the use of TRN may trigger this type of reaction, severe or moderate liver failure, severe kidney failure, diabetes, hyperthyroidism, a tumor of the adrenal gland (pheochromocytoma), a stomach ulcer, or esophagitis.
  • Nicorette Spray should not be used by non-smokers.
  • Refrain from eating or drinking while using the oral spray.
  • Take care not to spray the contents of the oral spray toward the eyes. If the spray comes into contact with the eyes, rinse thoroughly with water.
  • Keep out of the reach and sight of children.
  • Store at a temperature not exceeding 25°C.
  • Best used before the date indicated on the packaging.
  • Close the dispenser after each use to prevent children from using the mouth spray and to avoid accidental spraying.
  • Read the instructions before use.
  • Keep out of reach of children.
  • Store at a temperature not exceeding 25°C.

Taking Other Medications:
If you are taking or have recently taken any other medication, including over-the-counter medications, talk to your doctor or pharmacist. This is especially important if you are taking medications containing:

  • theophylline to treat asthma,
  • tacrine to treat Alzheimer’s disease,
  • clozapine to treat schizophrenia,
  • ropinirole to treat Parkinson’s disease.

Route of administration:Oral.

To increase your chances of success, read the package insert carefully, paying particular attention to the health education tips at the end of the insert.

Product Details 

Available in a value pack of two spray bottles, each containing 150 doses, at a discounted price, in mint flavor. Sold at the best price at your online organic pharmacy. 

Our Expert Pharmacy Advice

Instructions:

  • Press the top of the dispenser to release one dose into your mouth.
  • Do not inhale while spraying to prevent the product from entering your respiratory tract.
  • For best results, avoid swallowing for a few seconds after spraying.

Warnings Regarding Smoking Cessation Medications

Please note: Nicotine Spray is not like other products. Read the medication guide carefully before ordering. Keep medications out of the reach of children. If symptoms persist, consult your doctor or pharmacist. Be aware of potential interactions with your current medications.

  • Please inform your online pharmacist of any current treatments to identify potential interactions. The order confirmation form includes a custom message field for this purpose.
  • Click here to view the package insert for this medication on the website of the French National Agency for Medicines and Health Products Safety.
  • Pharmacovigilance: Report one or more adverse effects related to the use of a medication

Our advice and expert opinions from pharmacists

You probably already know that quitting smoking is an important decision to make if you want to protect your health, but you may be worried about the resulting nicotine withdrawal symptoms. These symptoms may appear two or three hours after your last cigarette, and they often peak after two or three days.

What should you do when you feel the urge to smoke?

  • Focus your attention on your breathing. Take a long breath in through your nose, count to 5, then exhale slowly through your mouth. Do this for 2 minutes
  • Drink a large glass of water. It’s recommended that you drink at least two liters of water throughout the day
  • Engage in a manual activity to counteract the physical craving
  • Chew sugar-free gum.
  • Brush your teeth
  • Call a friend to take your mind off things

Pharmacovigilance Report an adverse drug reaction(s)

Download PDF leaflet

NOTICE

ANSM - Updated on : 29/06/2023

Product name

NICORETTESPRAY 1 mg/dose, oral spray solution

Nicotine

Box

Please read this leaflet carefully before using this medicine, as it contains important information for you.

You must always use this medicine in strict accordance with the information given in this leaflet or by your doctor.

- Keep this leaflet. You may need to read it again.

- Ask your pharmacist for advice and information.

- If you experience any undesirable effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. See section 4.

- If you are unable to stop smoking after 6 months of treatment with NICORETTESPRAY, you should contact your doctor.

What does this leaflet contain?

1. What is NICORETTESPRAY 1 mg/dose, oral spray solution and what is it used for?

2. What do I need to know before using NICORETTESPRAY 1 mg/dose, oral spray solution?

3. How do I use NICORETTESPRAY 1 mg/dose, oral spray solution?

4. What are the possible side effects?

5. How do I keep NICORETTESPRAY 1 mg/dose, solution for mouth spray?

6. Package contents and other information.

1. WHAT IS NICORETTESPRAY 1 mg/dose, oral spray solution AND WHAT IS IT USED FOR?

NICORETTESPRAY is used to help smokers stop or reduce their tobacco consumption before they stop completely. It is a Nicotine Replacement Therapy (NRT) treatment.

NICORETTESPRAY relieves the symptoms of nicotine withdrawal experienced when quitting smoking, notably irresistible cravings. When the body is suddenly deprived of the nicotine provided by tobacco, it experiences various types of unpleasant sensations, known as withdrawal symptoms. NICORETTESPRAY helps prevent or reduce these unpleasant sensations and cravings. These effects are achieved thanks to the small amount of nicotine that the body continues to receive over a short period of time. NICORETTESPRAY is less harmful than smoking. It contains no tar, carbon monoxide or other toxins found in cigarette smoke.

To increase your chances of quitting smoking, take advantage of our advice and support service, if available.

2. WHAT DO I HAVE TO KNOW BEFORE USING NICORETTESPRAY 1 mg/dose, oral spray solution?

Never use NICORETTESPRAY 1 mg/dose, solution for mouth spray:

- if you are allergic to nicotine or to any of the other ingredients of this product, as listed in section 6.

- if you are under 18 years of age

- if you have never smoked

Warnings and precautions

Contact your doctor before taking this medicine if you experience any of the following symptoms. You may take NICORETTESPRAY, but you should discuss this with your doctor beforehand if you have :

- a recent history (< 3 months) of heart attack or stroke,

- chest pain (unstable angina pectoris), or stable angina pectoris,

- a heart problem affecting your heart rate or rhythm,

- high blood pressure not controlled by medication,

- a history of allergic reactions manifested by swelling of the lips, face and throat (angioedema) or an itchy rash (urticaria). The use of NRT may trigger this type of reaction,

- severe or moderate hepatic insufficiency,

- severe renal insufficiency

- diabetes,

- hyperthyroidism,

- a tumor of the adrenal gland (pheochromocytoma),

- stomach or duodenal ulcer,

- sophagitis,

- a history of seizures or convulsions.

NICORETTESPRAY should not be used by non-smokers.

Children and adolescents

Do not use in children or adolescents.

Other medicines and NICORETTESPRAY 1 mg/dose, oral spray solution

Tell your doctor or pharmacist if you are taking, have recently taken or may take any other medicines, including medicines obtained without a prescription. This is particularly important if you are taking medicines containing :

- theophylline to treat asthma,

- tacrine to treat Alzheimer's disease,

- clozapine to treat schizophrenia,

- ropinirole to treat Parkinson's disease.

NICORETTESPRAY 1 mg/dose, oral spray solution with food and drink

Do not eat or drink while spraying.

Pregnancy, breast-feeding and fertility

It is very important to stop smoking during pregnancy, as it can slow down your baby's growth. It can also lead to premature delivery or late fetal death. It is advisable to stop smoking without using nicotine-containing medication.

If you are unable to stop smoking without nicotine replacement therapy, NICORETTESPRAY may be used in consultation with the healthcare professional monitoring your pregnancy, your paediatrician or your pharmacist. who is monitoring your pregnancy, your family doctor, or a doctor at a center specializing in helping people who want to stop smoking.

The use of NICORETTESPRAY should be avoided while breast-feeding, as nicotine passes into breast milk and may affect your child. If your doctor has recommended that you use NICORETTESPRAY, the dose should be taken immediately after feeding, with a 2-hour interval between a mouth spray and the next feeding.

Smoking increases the risk of fertility in both men and women. The effects of nicotine on fertility are unknown.

Driving vehicles and using machines

No effect has been observed on the ability to drive vehicles and use machines.

NICORETTESPRAY contains 11 mg propylene glycol per spray. NICORETTESPRAY contains approximately 7 mg alcohol (ethanol) per spray, equivalent to 97 mg/ml. The amount in one spray is equivalent to less than 2 ml beer or 1 ml wine. The amount of alcohol contained in this medicine is unlikely to have a significant effect.

It also contains less than 1 mmol (23 mg) sodium per spray, making it essentially "sodium-free". Due to the presence of butylated hydroxytoluene, NICORETTESPRAY may cause local skin reactions (e.g. contact dermatitis), or irritation of the eyes and mucous membranes.

3. HOW DO I USE NICORETTESPRAY 1 mg/dose, solution for mouth spray?

Always use NICORETTESPRAY exactly as instructed in this leaflet, or as directed by your doctor or pharmacist. Check with your doctor or pharmacist if in doubt.

NICORETTESPRAY should not be used by persons under 18 years of age.

Ask your doctor for advice if you have not succeeded in reducing the number of sprays or your cigarette consumption after 6 weeks of treatment, or if you need to use NICORETTESPRAY for more than 6 months.
Normally, you can take NICORETTESPRAY for 3 months, but not for more than 6 months.

Instructions on how to use NICORETTESPRAY depend on whether you stop immediately or gradually reduce the number of cigarettes you smoke before stopping completely.

Immediate smoking cessation

The aim is to stop smoking immediately, and using the spray will relieve irresistible cravings.

Do not use more than 2 sprays per dose or 4 sprays over 16 hours. The maximum dose is 64 sprays over 16 hours in a 24-hour period.

Step 1: Weeks 1 to 6

Use 1 or 2 sprays at regular smoking times, or when you feel the urge to smoke. Start with one spray, and if the urge to smoke doesn't disappear after a few minutes, use a second spray. If 2 sprays are required, subsequent doses may comprise 2 consecutive sprays. Most smokers should use 1 or 2 sprays every 30 minutes to 1 hour.

For example, if you smoke an average of 15 cigarettes a day, you should use 1 to 2 sprays at least 15 times a day.

Step 2: Weeks 7 to 9

Start reducing the number of sprays per day.

By the end of Week 9, the average number of sprays you use per day should be HALF that of Step 1.

Step 3: Weeks 10 to 12

Continue to reduce the number of sprays per day until you reach a maximum of 4 sprays per day in Week 12. When you're down to 2-4 sprays a day, you can stop using NICORETTESPRAY.

Smoking cessation

The aim is to start by gradually replacing some of your cigarettes with NICORETTESPRAY. After that, you stop smoking cigarettes altogether when you use the spray. Finally, you stop using the spray.

When you feel an irresistible urge to smoke, use 1 to 2 sprays instead of a cigarette to help you manage your cravings. The spray is intended to replace a cigarette, so don't smoke immediately after using the spray. Using the spray without reducing the number of cigarettes you smoke may cause undesirable effects (see "If you have used more NICORETTESPRAY 1 mg/dose, oral spray solution than you should have"). Reduce the number of cigarettes you smoke per day as much as possible and replace them with a spray. If you have not succeeded in reducing your cigarette consumption after 6 weeks of treatment, seek advice from a healthcare professional. As soon as you feel ready, you can stop smoking completely, but no later than 12 weeks after the start of treatment. Once you've stopped smoking, gradually reduce the number of sprays per day. When you've reduced it to 2 to 4 sprays a day, you can stop using NICORETTESPRAY.

Do not use more than 2 sprays per dose or 4 sprays over 16 hours. The maximum dose is 64 sprays over 16 hours in a 24-hour period.

When treatment stops, you may be tempted to smoke again. Keep a spare spray bottle on hand, as the urge to smoke may suddenly reappear. If you have an irresistible urge to smoke, use one or two sprays if the effects of a single spray are insufficient after a few minutes.

Follow these instructions carefully, using the diagrams as a guide.

Releasing the spray orifice

Opening the dispenser

1. Using your thumb, slide the knob (a) downwards until you can push it in with light pressure (b). Do not press too hard.

2. While pushing the knob inwards, slide it upwards (c) to release the top of the dispenser. Then release the knob.

Loading the dispenser

When using the oral sprayer for the first time, start by priming the sprayer. Hold the sprayer away from yourself and nearby adults, children and pets. Using your index finger, press the top of the dispenser 3 times until a fine mist appears. After 2 days without use, it may be necessary to repeat this sprayer loading procedure.

Using the dispenser

3. Open your mouth and place the spray nozzle as close to it as possible.

4. Press firmly on the top of the sprayer to release a dose into your mouth, avoiding the lips. Do not inhale when spraying, to prevent the product from entering your respiratory tract. For best results, avoid swallowing for a few seconds after spraying.

Blocking the spray orifice

Closing the dispenser

5. Slide knob (d) down until it can be pushed in (e).

6. While pushing the knob inwards, slide the top part of the dispenser down (f). Release the button. The dispenser is now closed.

To take another dose, repeat the above steps.

Close the dispenser after each use to prevent children from using the sprayer and to avoid accidental spraying.

Take care not to spray the contents of the mouth spray into the eyes. If sprayed in eyes, rinse thoroughly with water.

If you have used more NICORETTESPRAY 1 mg/dose, oral spray solution than you should have

Nicotine overdose may occur if you smoke while using NICORETTESPRAY.

If a child is using NICORETTESPRAY, or if you have used more NICORETTESPRAY than you should have, contact your doctor or the nearest hospital immediately. The doses of nicotine tolerated by adult smokers during treatment can cause severe, even fatal, intoxication in children.

Symptoms of overdosage include nausea, vomiting, excess saliva, stomach pain, diarrhea, vomiting, diarrhea, nausea and vomiting.stomach pain, diarrhea, sweating, headache, dizziness, hearing loss and general weakness. At high doses, these symptoms may be accompanied by low blood pressure, weak and irregular pulse, difficulty breathing, extreme fatigue, cardiovascular collapse and convulsions.

If you have any further questions about the use of this drug, please ask your doctor or pharmacist.

4. WHAT ARE THE POSSIBLE SIDE EFFECTS?

Like all medicines, NICORETTESPRAY may cause undesirable effects, but these do not always occur in everyone.

NICORETTESPRAY may produce the same undesirable effects as other forms of nicotine. In general, side effects are related to the dose you take.

Effects related to smoking cessation (nicotine withdrawal)

Some of the side effects you experience when you stop smoking may be withdrawal symptoms due to reduced nicotine intake.

These include :

- irritability, aggressiveness, impatience or frustration,

- anxiety, restlessness or difficulty concentrating,

- insomnia or sleep disorders,

- increased appetite or weight gain,

- depressed mood,

- urge to smoke (cravings),

- reduced heart rate,

- bleeding gums or mouth ulcers

- dizziness or drunkenness,

- cough, sore throat, blocked nose or runny nose.

- constipation

If you notice any of these rare but serious side effects, stop taking NICORETTESPRAY and contact a doctor immediately (signs of angioedema):

- swelling of the face, tongue or pharynx,

- difficulty swallowing,

- hives and difficulty breathing.

Very common: affects more than 1 in 10 users

- hiccups (particularly frequent),

- headache, nausea (vomiting),

- throat irritation

Common: affects up to 1 in 10 users

- localized effects such as burning sensation, inflammation of the mouth, alteration of taste

- dry mouth or increased saliva,

- dyspepsia,

- pain or discomfort in the abdomen,

- vomiting, flatulence or diarrhea,

- feeling of tiredness,

- hypersensitivity (allergy)

- tingling

- cough

Uncommon: affects up to 1 in 100 users:

- effects on the nose such as blocked nose, sneezing

- wheezing (bronchospasm), or a feeling that breathing requires more effort than usual (dyspnea), throat tightness

- hot flushes (facial flushing), or excessive sweating,

- effects in the mouth such as tingling in the mouth, inflammation of the tongue, mouth ulcers, lesions of the oral mucosa, or changes in the sound of your voice, pain in the mouth and throat, belching, bleeding gums

- palpitations (unusual sensitivity to your heartbeat), increased heart rate, high blood pressure

- skin rashes and/or itching (pruritus, urticaria).

- nightmares

- chest discomfort and pain

- weakness, malaise

- runny nose

Rare: affects up to 1 in 1,000 users

- difficulty swallowing, decreased sensation in the mouth

- retching

Unknown frequency: frequency cannot be estimated on the basis of available data

- blurred vision, increased tear production (lacrimation)

- dry throat, stomach discomfort, sore lips

- skin redness

- allergic reactions including swelling of the face and mouth (angioedema or anaphylaxis).

- heart rhythm disorders

- convulsions

Reporting side effects

If you experience any side effects, please tell your doctor or pharmacist. This also applies to any side effect not mentioned in this leaflet. You can also report adverse reactions directly via the national reporting system: Agence nationale de sécurité du médicament et des produits de santé (ANSM) and the network of Centres Régionaux de Pharmacovigilance - Website: https://signalement.social-sante.gouv.fr.

By reporting adverse reactions, you contribute to providing more information on drug safety.

5. HOW TO CONSERVE NICORETTESPRAY 1 mg/dose, solution for mouth spray?

Keep out of sight and reach of children.

Do not use NICORETTESPRAY after the expiry date (EXP) indicated on the dispenser and outer packaging. The expiration date refers to the last day of the month.

Store at temperatures not exceeding 30°C.

Do not dispose of any medicine down the drain or in the household waste. Ask your pharmacist to dispose of any medicines you no longer use. These measures will help protect the environment, especially the aquatic environment in the case of nicotine.

6. CONTENTS AND OTHER INFORMATION

What NICORETTESPRAY 1 mg/dose oral spray solution contains

- The active substance is :

Nicotine.................................................................................................................................. 1 mg

for one spray.

- Other ingredients are :

Propylene glycol (E1520), ethanol anhydrous, trometamol, poloxamer 407, glycerol (E422), sodium bicarbonate, levomenthol, mint flavour, refreshing flavour.flavor, sucralose, acesulfame potassium, butylated hydroxytoluene (E321), hydrochloric acid (pH adjustment) and purified water.

What NICORETTESPRAY 1 mg/dose oral spray solution is and what it contains

NICORETTESPRAY is supplied as an oral solution in a plastic bottle contained in a dispenser fitted with a mechanical spray pump. The dispenser is child-resistant.

Each bottle contains 13.2 ml of solution to provide 150 doses, each containing 1 mg of nicotine.

NICORETTESPRAY comes in boxes of 1 or 2 dispensers.

All presentations may not be marketed.

Explanatory note: The 2 sentences between <> above referring to the presentation with the NFC chip will only be printed on the leaflet in countries where this presentation is available.

Marketing authorization holder

JOHNSON & JOHNSON SANTE BEAUTE FRANCE

43 RUE CAMILLE DESMOULINS

92130 ISSY-LES-MOULINEAUX, FRANCE

Marketing authorization holder

JOHNSON & JOHNSON SANTE BEAUTE FRANCE

43 RUE CAMILLE DESMOULINS

92130 ISSY-LES-MOULINEAUX

Manufacturer

MCNEIL AB

P.O. BOX 941

NORRBROPLATSEN 2,

SE-251 09 HELSINGBORG,

SWEDEN

Product names in member states of the European Economic Area

This product is authorized in the member states of the European Economic Area under the following names: In accordance with current regulations.

[To be completed subsequently by the holder].

The last date on which this leaflet was revised was :

[to be completed at a later date by the registrant]

Other

Detailed information on this drug is available on the ANSM (France) website.

HEALTH EDUCATION ADVICE :

Quitting smoking as soon as possible has immediate health benefits. It's never too late to quit, even if you've smoked a lot for a long time.

As soon as you stop smoking

- you will no longer absorb the irritating and toxic substances of cigarettes,

- you'll notice certain improvements: gradual disappearance of headaches, coughing, throat irritation and shortness of breath,

- you'll often enjoy the satisfaction of better sleep, food flavors and smells, and improved physical performance,

- reduce your risk of developing lung cancer or cardiovascular disease.

In the case of heart or arterial disease (angina pectoris, arteritis of the lower limbs), it is particularly important to succeed in quitting smoking.

What is tobacco dependence?

Tobacco addiction is twofold:

- Psychological dependence

Smoking a cigarette involves a ritual of automatic, repetitive gestures associated with particular circumstances (pleasure, response to stress, intellectual stimulation, support for morale, need for the gesture of conviviality). This is psychological and behavioral dependence.

- Physical dependence

The body's need for nicotine is due to its effects on the nervous system. This is physical dependence. Failure to satisfy this need leads to a feeling of craving (see description in the chapter "How to overcome your physical dependence? ").

Nicotine substitutes are designed to treat this dependence.

How to overcome your psychological dependence?

- To increase your chances of success, you need to stop smoking completely:

- choose a day when you feel most confident about quitting,

- throw away your last pack of cigarettes, your lighter and put away your ashtrays,

- In the case of a smoking couple, it's preferable for both partners to quit at the same time.

- Let your family and colleagues know that you're quitting smoking. Ask them to respect your decision (not to smoke near you, not to offer you any more cigarettes).

- Be prepared for the urge to smoke. It may come on suddenly and intensely, especially in the first few weeks after you've stopped smoking, but it shouldn't last more than 3 or 4 minutes.

You need to plan what you're going to do in that case, and act very quickly to avoid "cracking":

- drink a large glass of water,

- chewing gum,

- count to 100,

- take a few deep breaths,

- leave the room,

- change activity

Avoid situations associated with smoking (coffee, aperitifs, etc.), avoid temptations (sit with non-smokers).

Find ways to compensate for smoking (hobbies, sports, cultural activities).

How can you overcome your physical dependence?

If you're addicted to nicotine, you may need to use nicotine substitutes to succeed.

To assess your level of dependence, we suggest you take the Fagerström test.

FAGERSTROM TEST

How long after waking up do you smoke your first cigarette?

- within 5 minutes: 3

- 6 to 30 minutes: 2

- from 31 to 60 minutes: 1

- after 60 minutes: 0

Do you find it difficult not to smoke in places where it's forbidden?

- yes : 1

- no : 0

Which cigarette of the day would be the most difficult for you to give up?

- the first: 1

- another : 0

How many cigarettes do you smoke a day?

- 10 or less: 0

- 11 à 20 : 1

- 21 à 30 : 2

- 31 or more: 3

Do you smoke more in the morning than in the afternoon?

- yes : 1

- no : 0

Do you smoke when you are so ill that you have to stay in bed most of the day?

- yes : 1

- no : 0

TOTAL POINTS

Score from 0 to 2: you are not addicted to nicotine.

You can stop smoking without needing a nicotine substitute.

However, if you're worried about quitting, ask your pharmacist or doctor for advice.

Score of 3 to 4: you are mildly dependent on nicotine.

Score 5 to 6: you are moderately dependent on nicotine.

The use of nicotine substitutes will increase your chances of success.

Ask your pharmacist or doctor for advice on the best treatment for you.

Score of 7 to 10: you are strongly or very strongly dependent on nicotine.

The use of nicotine substitutes is recommended to help you overcome this nicotine dependence. This treatment must be used in sufficient and appropriate doses.

Ask your pharmacist or doctor for advice, possibly in the context of a specialized smoking cessation consultation.

Withdrawal symptoms may persist for a long time, and treatment should usually last one to three months.

If, despite treatment, you experience a persistent sensation of "craving", such as

- the urge to smoke

- irritability, sleep disturbances

- restlessness or impatience,

- difficulty concentrating.

Consult your doctor or pharmacist, as dose adjustments may be necessary.

How can we help you?

- Support from healthcare professionals

The support, advice and follow-up provided by your doctor or pharmacist will be invaluable during the first six months of quitting smoking. You can also turn to a specialized smoking cessation consultation, especially if you've already failed.

- Psychological support

Quitting smoking requires a supportive family and social environment. If you're worried that the difficulties are too great, psychological support or temporary treatment can help.

- Diet

In the months following smoking cessation, you may notice a moderate weight gain. If you have any concerns in this area, you can speak to a health professional who will be able to advise you.

Why have you started smoking again?

Think of this relapse as an accident along the way, as a normal learning event: a relapse is not a failure.

Analyze the reasons why you started smoking again.

- Physical dependence

This may not have been properly taken into account, or it may have reappeared after several months, for example, during prolonged stays in smoky atmospheres.

- Excessive weight gain

You may need to modify your eating habits a little before your next attempt to stop smoking.

- Because of a drop in motivation, a painful event or difficult period, or psychological difficulties that have arisen in the course of quitting smoking.psychological difficulties (depression, anxiety), or a very tempting situation. Understand the reason for this relapse, so you can prevent it if possible the next time you try.

In all cases, don't hesitate to ask a healthcare professional for advice, or seek out a specialized smoking cessation consultation.

If you've started smoking again, don't be discouraged. Experience shows that your chances of success increase after one or more quit attempts.

VIDAL DE LA FAMILLE

NICOTINE EG solution pour pulvérisation buccale

Fiche révisée le 15 Octobre 2020
Famille du médicament : Substitut nicotinique

Ce médicament est un générique de NICORETTESPRAY.

Indications

Ce médicament aide les fumeurs à se désintoxiquer du tabac. La solution apporte dans le sang par l'intermédiaire de la muqueuse buccale, la nicotine, principale substance active du tabac, responsable de l'accoutumance.

Présentations

NICOTINE EG 1 mg/dose : solution pour pulvérisation buccale (arôme menthe) ; boîte de 2 flacons pulvérisateurs de 15 ml
Ordonnance facultative - Remboursable à 65% - Prix : 17.55 €

Les prix mentionnés ne tiennent pas compte des « honoraires de dispensation » du pharmacien.

Composition

p pulv
Nicotine1 mg
Alcool+
Propylèneglycol+

Attention

Dans l'optique d'une désintoxication définitive, l'arrêt du tabac est une condition nécessaire au succès du traitement.

Des précautions sont nécessaires en cas de maladie cardiaque grave (infarctus du myocarde récent, angine de poitrine d'aggravation récente, angor de Printzmetal, troubles du rythme cardiaque grave, accident vasculaire cérébral), d'ulcère de l'estomac ou du duodénum, d'hyperthyroïdie, de phéochromocytome, de diabète, d'insuffisance rénale ou d'insuffisance hépatique. Dans ces situations, une consultation médicale préalable est indispensable avant d'utiliser ce médicament ; un arrêt du tabac sans traitement de substitution peut être nécessaire.

La nicotine est une substance toxique. Ne laissez pas le flacon à la portée des enfants. L'usage de ce médicament est réservé aux adultes de plus de 18 ans (en l'absence d'études).

Interactions médicamenteuses

Les produits contenus dans la fumée du tabac peuvent accélérer la vitesse d'élimination de certains médicaments, la théophylline notamment. Lors de l'arrêt du tabagisme, ces médicaments peuvent voir leur effet renforcé et des signes de surdosage peuvent apparaître. Contactez votre médecin au moindre doute.

Fertilité, grossesse et allaitement

Grossesse :

Le tabagisme chez la femme enceinte peut être à l'origine d'un retard de croissance du fœtus. L'arrêt du tabac est donc toujours souhaitable. Chez les femmes fortement dépendantes à la nicotine, l'usage de ce médicament peut être une aide, mais les effets de la nicotine seule sur le fœtus sont mal connus. Ce médicament a l'avantage de ne pas exposer le fœtus aux autres toxiques présents dans la fumée du tabac. En résumé : si l'idéal est de ne pas fumer et de ne pas exposer le fœtus à des apports de nicotine, l'usage de ce médicament est un moindre mal par rapport au tabac.

Allaitement :

La nicotine passe dans le lait maternel, l'allaitement est déconseillé pendant le traitement.

Mode d'emploi et posologie

La solution doit être pulvérisée dans la bouche en évitant les lèvres. Pour une meilleure efficacité, il faut éviter d'avaler sa salive dans les secondes qui suivant la pulvérisation.

En pratique, il est utile de connaître les signes de sous ou surdosage pour adapter la posologie après quelques jours de traitement :
  • le surdosage aboutit à l'état du fumeur qui a trop fumé et se traduit principalement par un état nauséeux et des maux de tête. Des troubles de la vue ou de l'audition, un tremblement, des vertiges sont également possibles ;
  • un sous-dosage provoque des symptômes de manque : irritabilité, nervosité, crampes d'estomac (sorte de faim douloureuse), difficulté de concentration.

Posologie usuelle :

  • Adulte : pendant une première phase de 6 semaines, faire une pulvérisation chaque fois que le besoin de fumer se fait sentir, soit en général 1 ou 2 fois par heure. Si l'envie persiste après quelques minutes, renouvelez la pulvérisation. Ne pas dépasser 2 pulvérisations par prise et 64 pulvérisations par jour.

    Une deuxième phase, qui dure habituellement 3 semaines, correspond à une diminution de moitié du nombre de pulvérisations par jour.

    Il faut ensuite continuer pendant quelques semaines à réduire le nombre de pulvérisations, jusqu'à désaccoutumance complète.

Ne pas dépasser 6 mois de traitement continu.

Conseils

Ce médicament peut être en accès direct dans certaines pharmacies et être utilisé sans consultation médicale. Néanmoins, n'hésitez pas à faire valider votre choix par votre pharmacien. Ses conseils sont précieux. Il pourra vous aider à déterminer le meilleur moment pour arrêter de fumer et vous expliquera les causes d'échec.

La nicotine prise par voie orale en remplacement de la cigarette présente la même nocivité cardiovasculaire que celle qui est contenue dans le tabac. Seul le risque de cancer du poumon disparaît. Lorsque l'arrêt du tabac est motivé par des raisons médicales urgentes : infarctus récent, artérite, gastrite ou ulcère, il est préférable d'arrêter l'absorption de nicotine sous toutes ses formes.

Comme toutes les méthodes antitabac utilisées pour aider les fumeurs, ce médicament ne peut être efficace que lorsque la volonté d'arrêter de fumer est personnelle et s'accompagne d'une forte motivation. C'est cette motivation qui permettra de lutter contre l'envie de fumer, sans être forcé de faire en permanence appel à la volonté qui s'émousse avec le temps. Un arrêt du tabac durable chez le fumeur suppose que celui-ci considère le tabac comme un poison, une dépendance inacceptable. Il doit se faire à l'idée qu'il ne fumera plus jamais, dès le début du sevrage. Chaque jour sans tabac doit être vécu comme une libération, et non comme un calvaire. Le fumeur qui est dans cet état d'esprit est un bon candidat au sevrage définitif.

L'arrêt du tabac, qui est une véritable drogue, induit de nombreux problèmes : une prise de poids est fréquente, des troubles de la concentration peuvent durer plusieurs semaines. Un état dépressif léger est possible. La prise de poids doit être combattue par un régime, et si possible par un programme sportif qui a l'avantage de réconcilier le fumeur avec son corps.

N'hésitez pas à consulter votre médecin en cas de difficulté ; ses conseils et son expérience seront précieux pour lutter contre les rechutes.

Effets indésirables possibles

Au cours des premiers jours de traitement, irritation de la bouche ou de la gorge et hoquet sont particulièrement fréquents. Ces effets s'atténuent habituellement à la poursuite du traitement.

Très fréquents (plus de 10 % des cas) : nausées, digestion difficile, salivation excessive ou au contraire bouche sèche, sensation de brûlure des lèvres, maux de tête, troubles du goût, inflammation de la muqueuse buccale.

Fréqents (1 à 10 % des cas) : vomissements, diarrhée, ballonnements, gorge serrée, fatigue.

Peu fréquents (moins de 1 % des cas) : fourmillements, larmoiement, palpitations, bouffées de chaleur, essoufflement, nez bouché ou qui coule, éternuements, gingivite, inflammation de la langue, sueurs, éruption cutanée, démangeaisons, enrouement, voix éraillée.

Rarement : vision floue, troubles du rythme cardiaque, réaction allergique.

LEXIQUE

accident vasculaire cérébral

Lésion du cerveau due à une hémorragie ou à l'obstruction brutale d'une artère. En fonction de l'importance de la lésion, les conséquences sont plus ou moins graves : malaise passager, paralysie, coma.

Abréviation : AVC.

Consultez l'article : Accident vasculaire cérébral (AVC)

accoutumance

L'accoutumance (ou tolérance) correspond à la diminution progressive de l'effet d'un médicament. Ce phénomène peut conduire à augmenter les doses pour maintenir une efficacité constante du traitement. L'accoutumance aggrave le risque de dépendance (besoin physique et/ou psychique de prendre un médicament).

alcool

Nom général désignant une famille de substances qui ont la propriété de pouvoir être mélangées à l'eau et aux corps gras. L'alcool le plus courant est l'alcool éthylique (éthanol), mais il existe de nombreux autres alcools : méthanol, butanol, etc. Le degré d'une solution alcoolique correspond au volume d'alcool pur présent dans 100 ml de solution, en sachant que 1 verre ballon de vin ou 1 demi de bière (25 cl) contiennent environ 8 g d'alcool.

Lorsque l'alcool est utilisé comme antiseptique, un dénaturant d'odeur désagréable lui est souvent ajouté pour éviter qu'il soit bu. Contrairement à une croyance répandue, l'alcool à 70° (ou même à 60°) est un meilleur antiseptique que l'alcool à 90°.

Consultez l'article : Alcoolodépendance

angine de poitrine

Douleur oppressante due à une obstruction partielle des artères coronaires qui irriguent le muscle cardiaque. Elle peut se manifester dans la poitrine, les bras ou la mâchoire.

Synonyme : angor.

angor

Douleur oppressante due à une obstruction partielle des artères coronaires qui irriguent le muscle cardiaque. Elle peut se manifester dans la poitrine, les bras ou la mâchoire.

Synonyme : angine de poitrine.

artérite

Maladie des artères favorisée par le tabagisme et le plus souvent localisée aux jambes. Elle se caractérise par un épaississement des parois artérielles qui gêne la circulation du sang et entraîne des douleurs au cours de la marche (claudication intermittente). L'artérite des membres inférieurs augmente le risque de survenue d'infarctus du myocarde et nécessite un traitement médicamenteux. À un stade évolué, elle peut être traitée chirurgicalement.

Synonyme : artériopathie oblitérante des membres inférieurs.

Consultez l'article : Artérite des jambes

ballonnement

Accumulation d'air ou de gaz dans l'intestin.

Consultez l'article : Ballonnement, flatulence et aérophagie

cancer

Maladie due au développement anarchique et incontrôlable de certaines cellules de l'organisme. Ces cellules anormales, capables de se multiplier indéfiniment, peuvent envahir des organes ou des vaisseaux sanguins et lymphatiques, formant à distance de nouvelles tumeurs, appelées métastases. On classe les cancers en tumeurs solides (qui se développent à partir d'un organe visible) et en tumeurs liquidiennes, qui proviennent des cellules de la moelle osseuse (leucémies notamment).

Consultez les articles : Les cancers

dépendance

Besoin psychique ou physique entraîné par la prise de certaines substances naturelles ou médicamenteuses. Cet état peut s'accompagner, à l'arrêt des prises, de symptômes variés, regroupés sous le terme de syndrome de sevrage.

diabète

Terme général désignant les maladies se traduisant par l'émission d'urines abondantes et par une soif intense. Employé seul, le mot diabète concerne généralement le diabète sucré, qui correspond à une perturbation de la régulation des sucres de l'organisme par l'insuline. Il se traduit par l'augmentation du sucre (glucose) dans le sang et par sa présence éventuelle dans les urines. Il existe deux sortes de diabète sucré : le diabète de type 1, ou insulinodépendant, qui nécessite un traitement par l'insuline en injection, et le diabète de type 2, ou non insulinodépendant, qui peut, dans un premier temps, être traité par les antidiabétiques oraux.

Consultez l'article : Diabète de type 1 ou Diabète de type 2

diarrhée

Le sens médical strict de diarrhée est « émission de selles trop fréquentes et trop abondantes ». En fait, le sens commun assimile la diarrhée à la notion de selles liquides et fréquentes. Normalement, les selles sont pâteuses, mais l'émission de selles liquides ou à peine formées, sans douleur ou trouble particulier associé, n'est pas pathologique. On peut parler de diarrhée lorsque les émissions de selles liquides se répètent dans la journée, et que les besoins sont impérieux ou douloureux.

Beaucoup de médicaments peuvent accélérer le transit intestinal et rendre les selles plus liquides, sans que cet effet indésirable soit réellement préoccupant.

Les antibiotiques peuvent altérer la flore digestive, indispensable à la digestion, et provoquer des diarrhées plus ou moins gênantes mais bénignes. L'effet apparaît immédiatement ou après quelques jours de traitement. Une forme de diarrhée grave et exceptionnelle, la colite pseudomembraneuse, peut être observée après un traitement antibiotique ; cette affection se traduit par l'émission de glaires et de fausses membranes (ressemblant à des lambeaux de peau) associées à des douleurs abdominales ; une constipation peut remplacer la diarrhée initiale. La colite pseudomembraneuse peut survenir plusieurs jours après l'arrêt du traitement antibiotique et nécessite un avis médical urgent.

Consultez l'article : Diarrhée et gastro-entérite de l’adulte ou Diarrhée et gastro-entérite de l’enfant

duodénum

Partie de l'intestin dans laquelle pénètrent les aliments issus de l'estomac.

éruption cutanée

Apparition de boutons ou de plaques sur la peau. Ces lésions peuvent être dues à un aliment, à un médicament, et traduire une allergie ou un effet toxique. De nombreux virus peuvent également provoquer des éruptions de boutons : celles de la rubéole, de la roséole et de la rougeole sont les plus connues.

état dépressif

État de souffrance morale associant une démotivation, une fatigue, un sentiment d'inutilité, d'autodépréciation. En l'absence de traitement, l'état dépressif risque d'évoluer vers une dépression grave avec sensation d'incurabilité, de culpabilité, et un risque suicidaire.

Consultez l'article : Déprime ou dépression ?

gastrite

Inflammation de l'estomac favorisée par le stress, le tabac, l'alcool et certains médicaments tels que l'aspirine ou les anti-inflammatoires.

générique

Médicament dont le brevet du principe actif est tombé dans le domaine public, permettant ainsi la commercialisation de copies du médicament original. Il présente la même composition qualitative et quantitative en principe(s) actif(s), la même forme pharmaceutique et la même biodisponibilité que le médicament original.

hyperthyroïdie

Excès d'hormones thyroïdiennes se traduisant notamment par une accélération du cœur, une mauvaise tolérance à la chaleur, un amaigrissement et une fatigue chronique.

Consultez l'article : Hyperthyroïdie

infarctus du myocarde

Destruction d'une partie du muscle cardiaque (myocarde), privé de sang par obstruction de ses artères.

Consultez l'article : Après un infarctus du myocarde

inflammation

Réaction naturelle de l'organisme contre un élément reconnu comme étranger. Elle se manifeste localement par une rougeur, une chaleur, une douleur ou un gonflement.

insuffisance hépatique

Incapacité du foie à remplir sa fonction, qui est essentiellement l'élimination de certains déchets, mais également la synthèse de nombreuses substances biologiques indispensables à l'organisme : albumine, cholestérol et facteurs de la coagulation (vitamine K, etc.).

insuffisance rénale

Incapacité des reins à éliminer les déchets ou les substances médicamenteuses. Une insuffisance rénale avancée ne se traduit pas forcément par une diminution de la quantité d'urine éliminée. Seuls une prise de sang et le dosage de la créatinine peuvent révéler cette maladie.

muqueuse

Tissu (membrane) qui tapisse les cavités et les conduits du corps communiquant avec l'extérieur (tube digestif, appareil respiratoire, voies urinaires, etc.).

palpitations

Perception anormale de battements cardiaques irréguliers.

Consultez l'article : Palpitations.

phéochromocytome

Tumeur très rare des glandes surrénales, se manifestant principalement par des crises d'hypertension artérielle.

posologie

Quantité et répartition de la dose d'un médicament en fonction de l'âge, du poids et de l'état général du malade.

réaction allergique

Réaction due à l'hypersensibilité de l'organisme à un médicament. Les réactions allergiques peuvent prendre des aspects très variés : urticaire, œdème de Quincke, eczéma, éruption de boutons rappelant la rougeole, etc. Le choc anaphylactique est une réaction allergique généralisée qui provoque un malaise par chute brutale de la tension artérielle.

Consultez l'article : Peut-on être allergique aux médicaments ?

surdosage

La prise en quantité excessive d'un médicament expose à une augmentation de l'intensité des effets indésirables, voire à l'apparition d'effets indésirables particuliers.

Ce surdosage peut résulter d'une intoxication accidentelle, ou volontaire dans un but de suicide : il convient alors de consulter le centre antipoison de votre région (liste en annexe de l'ouvrage). Mais le plus souvent, le surdosage est la conséquence d'une erreur dans la compréhension de l'ordonnance, ou de la recherche d'une augmentation de l'efficacité par un dépassement de la posologie préconisée. Enfin, une automédication intempestive peut conduire à l'absorption en quantité excessive d'une même substance contenue dans des médicaments différents. Certains médicaments exposent plus particulièrement à ce risque, car ils sont considérés (à tort) comme anodins : vitamines A et D, aspirine, etc. L'arrêt ou la diminution des prises médicamenteuses permettent de faire disparaître les troubles liés à un surdosage.

symptôme

Trouble ressenti par une personne atteinte d'une maladie. Un même symptôme peut traduire des maladies différentes et une même maladie ne donne pas forcément les mêmes symptômes chez tous les malades.

trouble du rythme cardiaque

Anomalie grave ou bénigne de la fréquence des contractions du cœur. L'extrasystole est une contraction survenant juste avant ou après une contraction normale, souvent perçue comme un léger choc dans la poitrine. La fibrillation est une contraction irrégulière et désordonnée. D'autres troubles existent : torsades de pointes, syndrome de Wolf-Parkinson-White, maladie de Bouveret, tachysystolie, flutter et bloc auriculoventriculaire, etc.

Consultez l'article : Troubles du rythme cardiaque.

ulcère

Lésion en creux de la peau, des muqueuses ou de la cornée.

  • Ulcère de jambe : plaie chronique due à une mauvaise circulation du sang.
  • Ulcère gastroduodénal : plaie localisée de la muqueuse de l'estomac ou du duodénum, due à un excès d'acidité et très souvent à la présence d'une bactérie (Helicobacter pylori). L'ulcère est favorisé par le stress, l'alcool, le tabagisme et la prise de certains médicaments (aspirine, AINS, etc.).
vertige

Symptôme qui peut désigner une impression de perte d'équilibre (sens commun) ou, plus strictement, une sensation de rotation sur soi-même ou de l'environnement (sens médical).

Consultez l'article : Vertiges.

voie
  • Chemin (voie d'administration) utilisé pour administrer les médicaments : voie orale, sublinguale, sous-cutanée, intramusculaire, intraveineuse, intradermique, transdermique.
  • Ensemble d'organes creux permettant le passage de l'air (voies respiratoires), des aliments (voies digestives), des urines (voies urinaires), de la bile (voies biliaires), etc.
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